Calcium dobesilate – a perfect stranger

Calcium Dobesilate – the Vasoactive Drug

CALCIUM DOBESILATE – PROMISING ROLE IN VASCULAR DISORDERS & HEMORRHOIDS. Calcium Dobesilate is a Capillotropic, Venotropic and Vasculoprotective Agent A Multi- Faceted Mechanism of Action

Calcium dobesilate may alleviate diabetes-induced endothelial dysfunction and inflammation

Diabetic kidney disease (DKD) is a leading cause of end‑stage renal disease. However, the pathogenesis of DKD remains unclear, and no effective treatments for the disease are available. Thus, there is an urgent need to elucidate the pathogenic mechanisms of DKD and to develop more effective therapies for this disease. Human umbilical vein endothelial cells (HUVECs) were cultured using different...

Combined treatment of diabetic nephropathy with alprostadil and calcium dobesilate

This study investigated the effects of alprostadil combined with calcium dobesilate on the treatment of diabetic nephropathy. We recruited 80 patients with diabetic nephropathy, who were randomly divided into experimental (n=40) and control (n=40) groups. Patients received high-quality low-protein diabetic diet intervention and subcutaneous injection of insulin to adjust blood glucose, combined...

Calcium dobesilate for prevention of gentamicin-induced nephrotoxicity in rats.

INTRODUCTION Calcium dobesilate is an antioxidant drug and this study is aimed to investigate the effects of calcium dobesilate on gentamicin-induced nephrotoxicity. MATERIAL AND METHODS This experimental study was conducted on 40 male Sprague-Dawley rats. The rats were randomly divided into the following 5 groups: control, sham, gentamicin (100 mg/kg/d, intraperitoneal), gentamicin and calci...